Hyperbaric Oxygen Therapy (HBO) involves breathing pure oxygen in a sealed environment at higher than 1 atmospheric pressure, which significantly increases oxygen concentration in blood and tissues, fundamentally addressing key issues in postoperative recovery.
I. Core Mechanisms
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Rapidly and greatly increase tissue oxygen partial pressure
- Under normal pressure, oxygen is mainly carried by hemoglobin.
- Hyperbaric oxygen allows a large amount of oxygen to be directly dissolved in plasma.
→ Oxygen content in tissues increases by several to more than ten times.
→ Solves the core problem of postoperative ischemia and hypoxia.
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Reduce edema and improve microcirculation
- Constrict blood vessels and relieve tissue swelling.
- Improve capillary perfusion and reduce congestion.
→ Lower wound tension and facilitate healing.
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Promote fibroblast proliferation and collagen synthesis
- Adequate oxygen is essential for the proliferation of fibroblasts and epithelial cells.
- Promote collagen synthesis and angiogenesis.
→ Accelerate wound healing and incision healing.
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Enhance anti-infective ability
- Improve the phagocytic capacity of leukocytes.
- Inhibit the growth of anaerobic bacteria.
→ Reduce the risk of postoperative infection.
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Alleviate ischemia-reperfusion injury
- Scavenge oxygen free radicals.
- Protect cell membranes and reduce cell necrosis.
→ Particularly beneficial for trauma, skin grafting, replantation of amputated digits, etc.
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Promote nerve repair
- Improve oxygen supply to nerve tissues.
- Relieve nerve edema and promote myelin sheath repair.
→ Facilitate postoperative recovery of neurological function.
II. Overall Effects on Postoperative Repair
- Faster and firmer wound healing
- Significant reduction of swelling and pain
- Lower infection risk
- Improved survival of ischemic tissues, skin flaps and grafts
- Reduction of scar hyperplasia and complications